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anti-aging

How Fitness and Nutrition Crafts Longevity

How Fitness and Nutrition Crafts Longevity

When it comes to the pursuit of a longer, healthier life, there are few factors as crucial as fitness and nutrition. These two pillars of well-being are essential for feeling great today and increasing your chances of enjoying a vibrant

DCoello December 8, 2023October 11, 2024 Age hacking, Aging, Nutrition in Healthy Aging Read more

Who are the Leading Longevity Researchers

Who are the Leading Longevity Researchers

It’s tough to pinpoint a single individual as the “leading” longevity researcher, as the field is highly interdisciplinary, and numerous scientists and researchers have made significant contributions. However, several scientists and institutions have been prominent in longevity research: Dr. David

DCoello September 28, 2023November 22, 2023 Age hacking, Aging Read more

What are the Longevity Genes

What are the Longevity Genes

Longevity genes, often called “longevity-associated genes” or “longevity-related genes,” are specific genes associated with an increased likelihood of living longer or a reduced risk of age-related diseases. These genes play a role in various biological processes and pathways influencing aging

DCoello September 28, 2023September 28, 2023 Age hacking, Aging, Geroscience, reverse age Read more

Is hair color determined by genetics

reverse aging hair

Hair color is determined by the amount of a pigment called melanin. An abundance of one type of melanin, called eumelanin, gives people black or brown hair. An abundance of another pigment, called pheomelanin, gives people red hair. Hair color

DCoello July 5, 2023December 14, 2023 Age hacking, Aging Read more

Targeting NAD+ Metabolism as Interventions for Mitochondrial Disease

Targeting NAD+ Metabolism as Interventions for Mitochondrial Disease

Abstract Leigh syndrome is a mitochondrial disease characterized by neurological disorders, metabolic abnormalities, and premature death. There is no cure for Leigh syndrome; therefore, new therapeutic targets are urgently needed. In Ndufs4-KO mice, a mouse model of Leigh syndrome, we

DCoello June 7, 2023December 14, 2023 Journals Read more

Can follistatin enhance muscle growth?

follistatin

Follistatin is a protein that our body makes naturally. Your body uses it to control metabolism, grow muscle, and boost fertility. Increasing follistatin can help you put on muscle quickly and may help you burn a significant amount of body fat.

DCoello August 31, 2022December 15, 2023 Age hacking, Aging Read more

What is Myostatin, and what does it do?

Myostatin is a protein found almost exclusively in muscles used for movement (skeletal muscles), where it is active both before and after birth. This protein typically limits muscle growth, ensuring muscles do not grow too large. The MSTN gene provides instructions for making

DCoello August 31, 2022August 31, 2022 Age hacking, Aging, gene editing, gene therapy Read more

Can the body’s biological age be reversed?

reverse aging

In a small trial, drugs seemed to rejuvenate the body’s ‘epigenetic clock,’ which tracks a person’s biological age. A small clinical study in California has proposed for the first time that it might be possible to reverse the body’s epigenetic

DCoello August 14, 2022August 14, 2022 Age hacking, Aging, Chronological age vs. biological age, reverse age Read more

Long-Term Administration of Nicotinamide Mononucleotide Mitigates Age-Associated Physiological Decline in Mice

Highlights •NMN suppresses age-associated body weight gain and enhances energy metabolism •NMN improves insulin sensitivity, eye function, and other features with no toxicity •NMN prevents age-associated gene expression changes in a tissue-specific manner •NMN is an effective anti-aging intervention that

DCoello July 29, 2022July 29, 2022 Age hacking, Aging Read more

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Our mission is to research and develop permanent solutions to slow, stop, and reverse aging and aging-related diseases at the cellular level through biomedicine, gene therapy, data analytics, and AI, thus extending life and health span and enabling a better quality of life for older adults.

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