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Who are the Leading Longevity Researchers

Who are the Leading Longevity Researchers

It’s tough to pinpoint a single individual as the “leading” longevity researcher, as the field is highly interdisciplinary, and numerous scientists and researchers have made significant contributions. However, several scientists and institutions have been prominent in longevity research: Dr. David

DCoello September 28, 2023November 22, 2023 Age hacking, Aging Read more

The Science Behind NMN–A Stable, Reliable NAD+Activator and Anti-Aging Molecule

anti-aging

In June 2018, the World Health Organization (WHO) released the 11th edition of its International Classification of Diseases and added aging for the first time. The classification of aging as a disease paves the way for new research into novel therapeutics to

DCoello June 7, 2023June 7, 2023 Journals Read more

Targeting NAD+ Metabolism as Interventions for Mitochondrial Disease

Targeting NAD+ Metabolism as Interventions for Mitochondrial Disease

Abstract Leigh syndrome is a mitochondrial disease characterized by neurological disorders, metabolic abnormalities, and premature death. There is no cure for Leigh syndrome; therefore, new therapeutic targets are urgently needed. In Ndufs4-KO mice, a mouse model of Leigh syndrome, we

DCoello June 7, 2023December 14, 2023 Journals Read more

The Biology of Slowing & Reversing Aging | Huberman Lab Podcast 52

In this episode, Dr. Andrew Huberman is joined by Dr. David Sinclair, a tenured Professor of Genetics at Harvard Medical School and an expert researcher in longevity. Dr. Sinclair is also the author of Lifespan: Why We Age & Why

DCoello August 4, 2022August 4, 2022 Aging, Geroscience, Nutrition in Healthy Aging Read more

The Interplay Between Aging and Disease

The Interplay Between Aging and Disease

Dr. Felipe Sierra discusses the concept of geroscience, which focuses on the relationship between aging and age-related diseases. He emphasizes the significant increase in human lifespan but also highlights the problem of increased health issues in older individuals. Traditional medicine

DCoello July 31, 2022December 15, 2023 Aging, Geroscience Read more

Long-Term Administration of Nicotinamide Mononucleotide Mitigates Age-Associated Physiological Decline in Mice

Highlights •NMN suppresses age-associated body weight gain and enhances energy metabolism •NMN improves insulin sensitivity, eye function, and other features with no toxicity •NMN prevents age-associated gene expression changes in a tissue-specific manner •NMN is an effective anti-aging intervention that

DCoello July 29, 2022July 29, 2022 Age hacking, Aging Read more

NAD+ in Aging: The Roles of NR and NMN

NAD+ in Aging: The Roles of NR and NMN

Rhonda delves into NAD+: its importance for aging, its decline as we age, and popular NAD+ enhancers like nicotinamide riboside and nicotinamide mononucleotide. NAD+ is vital for survival, with small dietary contributions, but the body mainly recycles it. Everyday life

DCoello July 29, 2022December 15, 2023 Age hacking, Aging Read more

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Our mission is to research and develop permanent solutions to slow, stop, and reverse aging and aging-related diseases at the cellular level through biomedicine, gene therapy, data analytics, and AI, thus extending life and health span and enabling a better quality of life for older adults.

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